The Don Margolis Blog
Featuring the most comprehensive collection of "disease specific" stem cell treatment articles in the world. We provide the most current, factual and comprehensive information on available stem cell treatments today for your specific medical condition.
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A friend asked:
when are they going to allow us to use stem cells for autism in this country??? I am getting impatient every treatment center I’ve called here (in the US) says they wont do it! I am having a baby in feb and want to use the cord blood for my son but when will I ever be able to? anyone know?
WHY NO STEM CELLS IN THE US (FOR AUTISM)? – http://repairstemcell.wordpress.com/why-no-stem-cells-in-the-us/
STEM CELLS FOR AUTISM – PROGRESS TO DATE – http://repairstemcell.wordpress.com/2009/10/26/stem-cells-for-autism/
POTENTIAL OF STEM CELL TREATMENTS FOR AUTISM – http://repairstemcell.wordpress.com/2009/10/16/potential-of-stem-cell-treatments-for-autism/
TREATMENTS AVAILABLE TODAY – Asperger’s is an Autism Spectrum Disorder. To see if you or your loved one might be a candidate for Stem Cell Therapy, click here:http://repairstemcells.org/Treatment/Treatment-Request.aspx?d=Autism
CDC VACCINE COVER UP – MERCURY ACTUALLY DOES CAUSE AUTISM? Central Figure in CDC Vaccine Cover-Up Absconds With $2M
Posted:
2/10/2011 9:42:44 AM by
Don Margolis | with
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Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our
treatment form or email me
don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
| COST BY DISEASE |
# OF PATIENTS |
COST PER YEAR |
| TYPE 1 DIABETES |
5.8 MILLION PATIENTS |
$125.1 BILLION |
| STROKE |
5.7 MILLION PATIENTS |
$62.7 BILLION |
| HEART FAILURE |
5.2 MILLION PATIENTS |
$50.7 BILLION |
| SPINAL CORD INJURY |
250,000 PATIENTS |
$37.2 BILLION |
| PARKINSON’S DISEASE |
650,000 PATIENTS |
$23 BILLION |
TOTAL COST THAT ADULT STEM CELLS COULD SAVE THE UNITED STATES
$250 BILLION PER YEAR
Posted:
2/9/2011 9:44:44 AM by
Don Margolis | with
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Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our
treatment form or email me
don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
CATCH UP! They’ve been treating SCI patients successfully with stem cells for years now!
Stem cells may hold secret to multiple spinal injury repair
21 January 2011
Scientists may soon be able to repair multiple aspects of a spinal cord injury in humans, using adult stem cells.
A Case Western Reserve University School of Medicine study involving rats showed that use of multipotent adult progenitor cells (mapc) could prevent neuron retraction, promote new neuron re-growth and reduce inflammation in spinal injury.
Researchers will no doubt be hopeful that the development of such treatment can contribute significantly to reducing the costs of spinal injury treatment, which can range between $500,000 (£312,000) and $3 million (£1.9 million) in the US.
Commenting on the findings, published in the Journal of Neuroscience, university professor Jerry Silver explained: “Using preclinical models of spinal cord injury, we found that MAPC can both dynamically regulate macrophages, which cause inflammatory damage, and stimulate neuron growth simultaneously.
“Our results demonstrate that MAPC convey meaningful therapeutic benefits after spinal cord injury.”
Meanwhile, recent research conducted at Otago University suggests that cell tissue extracted from the nose could be transplanted to the site of spinal cord injury.
Scientists are hopeful the procedure could overcome blocks that prevent nerve cells regenerating following damage.
News by Serious Law. Expert legal assistance for those affected by spinal injury
Posted by Timothy Walters
Posted:
2/8/2011 4:31:41 PM by
Don Margolis | with
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Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our
treatment form or email me
don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
Recently, two New Zealand “experts” in the field of spinal cord injuries weighed in on stem cell treatments. One of them, Dr Richard Acland, Christchurch’s Burwood Hospital director of the spinal injuries unit, told TV ONE’s Breakfast today that he has concerns about stem cell treatments and their ability to help SCI patents recover. The other, “Spinal Cord Society president Noela Vallis said the procedure has been carried out overseas on well over 100 people with few negative side-effects and varying degrees of improvement for each patient.” via
Well done Noela! It is obvious to me that you are familiar with and have based your optimism on these articles…and it is further obvious that Dr Acland has never seen any of them:
SPINAL CORD INJURY vs ASC HISTORY OF TREATMENT – http://tinyurl.com/SCIvsASC
Stepping Towards A Paralysis Cure, A Tale Of Two Supermen Stem Cells Cure 23 Year Old Male of Paralysis – C6…-C7 injury
http://repairstemcell.wordpress.com/2009/03/28/stepping-towards-a-paralysis-cure-a-tale-of-two-supermen-stem-cells-cure-23-year-old-male-of-paralysis-c6-c7-injury/
Paraplegic – Adult Stem Cell Success Stories – Laura Dominguez
http://repairstemcell.wordpress.com/2010/05/05/paraplegic-adult-stem-cell-success-stories-laura-dominguez/
PARALYZED COUSINS PLEASED WITH STEM CELL TREATMENT
http://repairstemcell.wordpress.com/2010/02/15/paralyzed-cousins-pleased-with-stem-cell-treatment/
Successful Stem Cell Treatment of Spinal Cord Injury in Dogs
http://repairstemcell.wordpress.com/2010/02/08/successful-stem-cell-treatment-of-spinal-cord-injury-in-dogs/
Spinal Cord Injury Patient Wins…and Loses
http://repairstemcell.wordpress.com/2010/02/08/spinal-cord-injury-patient-wins-and-loses/
STEM CELLS FOR SPINAL CORD INJURY
http://repairstemcell.wordpress.com/2009/12/31/stem-cells-for-spinal-cord-injury/
Adult Stem Cell Grafts Help Paralyzed Heal
http://repairstemcell.wordpress.com/2009/10/21/adult-stem-cell-grafts-help-paralyzed-heal/
Medical hope as paralysed dog cured by stem cell therapy – mirror.co.ukhttp://repairstemcell.wordpress.com/2009/10/08/medical-hope-as-paralysed-dog-cured-by-stem-cell-therapy-mirror-co-uk/
Major the Roseville police dog gets stem cell treatment - http://blogs.citypages.com/blotter/2011/01/major_police_dog_stem_cell.php
and these 43 articles:
http://donrmargolis.com/Home/Blog.aspx?tagname=Spinal+Cord+Injury
Posted:
2/7/2011 4:21:42 PM by
Don Margolis | with
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Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our
treatment form or email me
don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
CATCH UP! This is laughable.
They want to make drugs for heart disease to do what stem cells have been doing for years! Here’s where they are: “…within the next decade they may have experimental drugs in development that would give certain… kinds of cells in the heart the ability to regenerate tissue, repair damage and therefore combat heart failure….” and “…his researchers had already had some success in using this protein to “wake up” cells known as epicardial cells in mice with damaged hearts.”
WHAT A JOKE!
1. Thousands of heart disease patients have been treated successfully around the world at stem cell treatment centers since 2004.
2. Prof Doris Taylor proved heart tissue can regenerate with stem cells in the 1990′s, built rodent and human hearts from scratch and opened a lab in Spain that grows entire hearts from the patient’s own stem cells last year.
CATCH UP ALREADY!
Scientists look to stem cells to mend broken hearts
LONDON | Tue Feb 1, 2011 4:14am EST
LONDON (Reuters Life!) – Britain’s leading heart charity launched a 50 million pound ($80 million) research project on Tuesday into the potential of stem cells to regenerate heart tissue and “mend broken hearts”…
Posted:
2/4/2011 4:05:49 PM by
Don Margolis | with
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Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our
treatment form or email me
don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
A stem cell transplant using her baby brother’s cord blood cells has cured Harshita Aggarwal, 8, of thalassaemia — a rare genetic blood disease that affects 1.7 lakh people, forcing them to undergo blood transfusions regularly. In India, this is the second time a child has been cured of this lifelong blood disorder using cord blood cells. So far, the only treatment available treatment in India was a bone marrow transplant. “In the normal process, if there's a damaged tissue, stem cells come into action and start rebuilding it. What we are trying is to increase the concentration of stem cells in the body to help the rebuilding process,” said Dr Naresh Trehan, chairman, Medanta-The Medicity.
Aggarwal received cord blood stem cells from her brother, Yuvraj, 2, whose cord blood was preserved at birth for treating Harshita, who is in Delhi with her grandmother Krishna Aggarwal.
“About a couple of years ago, when I was in Delhi for Harshita's treatment, I happened to see an article on cord blood stem cell banking and how it could help cure certain blood-related diseases. I contacted people at Cryobanks International India, who told me everything about stem cell banking. So, when my daughter-in-law conceived again, we decided to preserve the cord blood cells,” said Krishna Aggarwal, 62, who travelled to Delhi for transfusions every month for eight years, from her hometown in Patna, Bihar.
Dr Dharma Chaudhary, a transplant physician at Cryobanks International India, administered the treatment in December 2009.
“We waited a year because the treatment can be called a success only if the body does not reject the implanted cells for one year,” he said.
“Blood from a newborn's discarded umbilical cord is saved after birth because it is the richest source of stem cells. These cells can be saved for 21 years and used to treat genetic diseases, if the need arises. After the transplant, patients only take immuno-suppressant drugs to avoid rejection of the implanted foreign cells,” said Dr Chaudhary.
Cord blood stem cells can be banked at a monthly cost of R3,500 for 21 years. Later, the contract can be renewed. A stem cell transplant surgery costs about R14 lakh in India, which is one-tenth the cost in the US, where it costs R1.5 core.
“Less than 1% of India's population knows of it at the moment. It is an expensive proposition presently, but we are in the process of creating a public stem cell bank, which will bring down the cost,” said Ravi Jaipuria, chairman, RJ Corp, that owns Cryobanks International India.
Posted:
2/1/2011 12:38:50 PM by
Don Margolis | with
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Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our
treatment form or email me
don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
Tampa, Fla. (Jan. 10, 2011) – Transplanting their own (autologous) bone marrow-derived stem cells into 48 patients with end-stage liver disease resulted in therapeutic benefit to a high number of the patients, report researchers publishing in the current issue of Cell Transplantation (19:11). Yet, the mechanism by which the infusion of CD34+ stem cells improves liver function remains elusive, they say.
The study, carried out by a team of researchers in California and in Egypt, is now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/.
According to the study's corresponding author, Dr. Mark A. Zern of the University of California Davis Medical Center, Sacramento, CA, patients with end-stage liver failure in Egypt have few treatment options but for transplantation. A shortage of donors and cost factors make that strategy unrealistic. Accordingly, this study sought to evaluate the safety and efficacy of transplanting autologous bone marrow-derived CD34+ stem cells in 48 patients, 36 of whom had chronic, end-stage hepatitis C-induced liver disease, and 12 with end-stage autoimmune liver disease.
"For all patients there was a statistically significant decrease in peritoneal cavity fluid, or 'ascites,'" said Dr. Zern. "There was also clinical and biochemical improvement in a large percentage of patients who received the transplantation."
The researchers reported that they obtained "reasonable numbers of CD34+ cells" that were then "amplified and partially differentiated into hepatocyte precursor cells."
"This enabled us to transplant as many as one billion of these cells per patient," explained Dr. Zern. "The finding of improvement in ascites in a significant number of patients is impressive and somewhat surprising, suggesting that cell transplantation might be clinically significant beyond the improvement in laboratory parameters."
They also report using granulocyte-colony stimulating factor (G-CSF) to "mobilize…CD34+ stem cells into peripheral circulation." The researchers anticipated that G-CSF would likely enhance a variety of circulating bone marrow-derived cells, producing growth factors which could "positively affect liver regeneration and perhaps have a positive effect on portal hypertension."
The team also reported that prior to transplantation, the cells were already beginning to develop a hepatocyte phenotype while in culture, suggesting that the cells may have acted as hepatocyte-like cells following engraftment. The researchers plan to compare routes of infusion to determine if peripheral infusion of transplanted cells will be adequate.
"The use of peripheral infusion would dramatically reduce both costs and risks for this cell transplantation, thus making the treatment an even more viable option in Egypt and throughout the world," concluded Dr. Zern.
"It would be very interesting to determine if the differentiation to hepatic precursors was a necessary step for this treatment," said Dr. Stephen Strom, a professor of pathology in the Department of Pathology at the University of Pittsburgh and section editor for Cell Transplantation. "Other research groups are now showing similar results with cells without any hepatic characteristics, including fractionated and unfractionated bone marrow and mesenchymal stem cells. Taken together, these data suggest that the positive effects these researchers find may be the result of paracrine effects from factors secreted by the donor cells. I look forward to reading about the outcome of future studies to determine the optimal route of administration and dose of these cells, as well as more long term follow up."
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Contact: Dr. Mark A. Zern, UC Davis Medical Center, 4635 Second Ave. Ste. 1001, Sacramento, CA
Tel: (916) 734-8063; Fax: (916) 734-8097
Email: mazern@ucdavis.edu
Citation: Salama, H.; Zekri, A-R..; Zern, M.; Bahnassy, A.; Loutfy, S.; Shalaby, S.; Vigen, C.; Burke, W.; Mostafa, M.; Medhat, E.; Alfi, O.; Huttinger, E. Autologous Hematopoietic Stem Cell Transplantation in 48 Patients With End-Stage Chronic Liver Diseases. Cell Transplant. 19(11):1475-1486; 2010.
Posted:
1/14/2011 2:45:16 PM by
Don Margolis | with
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Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our
treatment form or email me
don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
Repair Stem Cells from Cord Blood Enhance Aging Brain Cells
by David Prentice
Researchers from the University of South Florida have shown that Repair (adult) Stem Cells from human umbilical cord blood can
enhance the survival and maturation of brain neurons from both young and old laboratory animals. The research may have implications for degenerative diseases of the brain, as well as for brain trauma.
The study was done in the laboratory using neurons taken from a specific area of the brain–the hippocampus. According to Dr. Alison Willing, senior author of the study:
“As we age, cognitive function tends to decline. Changes in cognitive function are accompanied by changes in the hippocampus, an area of the brain where long term memory, as well as other functions, are located, an area of the brain among those first to suffer the effects of diseases such as Alzheimer’s disease.”
The aging population is more susceptible to the stresses and diseases that affect this part of the brain. Interestingly, the positive effects of adult stem cells from cord blood were more pronounced with neurons from older animals. In addition, not only were the cord blood stem cells able to protect and stimulate growth of the neurons, they also stimulated growth of cells known as dendrites, the branching neurons which act as signaling nerve communication channels.
Posted:
12/16/2010 4:19:06 PM by
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Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our
treatment form or email me
don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
TOPEKA DOGS AGING BACKWARDS AFTER STEM CELL PROCEDURE
Gunner is leading the way for dogs in pain to live a new life. His owner Carrie Hoffman says, "He's like a puppy again. I can't keep up with him. It's wonderful." His buddy Sherman is proving you can't keep an old dog down. Sherman's owner Bruce Zimmerman says, "He's doing things that he hasn't done for a couple of years. Gets on the couch willingly."
Both dogs were the first in the state of Kansas to have their own stem cells injected back into their bodies. Their owners say it seems as if the dogs are now aging backward. Gunner used to drag his feet when he walked from pain in his joints. Now Hoffman says, "Our forth day after the procedure, he picked his feet up and he was prancing and later on that evening he decided to jump up on the sofa." Sherman's arthritis was so bad he even had a hard time taking care of business. Zimmerman says, "I think it was around day 10, he actually stood on his left leg and peed and it was a pretty major event around our house."
Just one month after the procedure, their vet couldn't be more pleased. UAC Veterinarian Larry Snyder says, "We've been very impressed with what these dogs are doing. Neither dog seems to be in any pain, they're moving well. It's almost like somebody turned back the hands of time."
Both owners say this procedure was their dogs' last chance at a quality of life they deserve. Hoffman says, "It's like an answer to my prayers because he's my baby. He's my baby. He might be big, but he's my big baby. The vet also noticed a growth on Sherman's nose has gotten visibly smaller since the procedure. He says they may not even know yet all of the benefits these dogs will see.
For the article plus videos:
The article explains that people call the animal clinic to see if they can get the procedure done on themselves. They cannot. FDA and PhRMA want you to buy their useless pills, knowing that humans are not smart enough to realize that their doctors’ pills make them nothing but worse.
Humans get the same good results as these animals if they are smart enough to realize where years of arthritis pills have gotten them (sicker than ever) and try stem cells also. Where? Ask us. If you are far gone, even stem cells won’t help but we know what will. If you are not far gone, we know where the stem cells are in North America. Just drop an email to
don@RepairStemCells.org with the subject: TREATMENT and the disease description in the message.
Posted:
12/16/2010 3:47:12 PM by
Don Margolis | with
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Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our
treatment form or email me
don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
Kansas Boy heads to Central America to treat “Untreatable” disease:
DUCHENNE’S MUSCULAR DYSTROPHY
Over the past year, Byrum Bittel has dropped 50 to 75 pounds. He’s lost strength in his arms, and routine tasks have become more difficult. But he’s hoping an upcoming operation will help turn things around. The 15-year-old Spearville boy suffers from Duchenne muscular dystrophy, a genetic disorder that affects about 1 in 3,500 boys around the world. People with DMD experience progressive loss of muscle function and weakness, starting in their lower limbs and spreading to the arms, neck and other areas. Few people with DMD live past their 30s, and breathing complications and cardiomyopathy — an enlarged heart — are common causes of death, according to the National Human Genome Research Institute. Byrum’s family knows there is no cure for the disease, but they are praying his upcoming surgery will buy him a few more years. The family learned recently that Byrum is eligible for a stem-cell transplant, an experimental treatment aimed at stopping the progress of his disease. The treatment will begin Jan. 31 at the Stem Cell Institute in Panama City, Panama. Byrum’s mother, Amanda Bittel, acknowledged that the transplant may not succeed in stopping the disease. But she said she’s keeping her fingers crossed. “There’s risk there,” she said in an interview Friday. “But considering there’s no other cure for Duchenne, we’re willing to take that risk.”
Deadly disorder - The first clue that Byrum had DMD came when he was only 8 months old. Byrum had been in and out of the hospital with croup and pneumonia, and his lab work showed his liver enzymes were higher than normal — which might have indicated a liver disease. Byrum’s local doctor wanted to send him to a specialist in Denver. But before the family drove to Denver, the doctor checked Byrum’s muscles and heart, which indicated that he had muscular dystrophy. But the family did not know whether Byrum had Duchenne or Becker’s muscular dystrophy — a less common and slower-moving form of the disease. A muscle biopsy when Byrum was 3 years old revealed the truth: He was suffering from DMD. “It was devastating,” Amanda Bittel said. Byrum’s doctors thought he would be confined to a wheelchair by the time he reached third grade, but he managed to defy the odds for two more years.
FOR FULL ARTICLE FROM THE DODGE CITY DAILY GLOBE:
http://www.dodgeglobe.com/news/x1966826711/Spearvilles-Byrum-Bittel-prepares-for-stem-cell-transplant
Posted:
12/1/2010 9:52:06 AM by
Don Margolis | with
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