The Don Margolis Blog

We would like to strongly suggest that our readers should apply for this clinical trial if they or a loved one has critical limb ischemia (CLI)   (usually caused by diabetes)

Stem Cell Research: Researcher transplants stem cells to try to ...
A Northwestern University Feinberg School of Medicine researcher has launched the first US trial in which a purified form of subjects' own adult stem cells was transplanted into...
NewsRx Latest News - http://www.newsrx.com

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Still ANOTHER source of ASC discovered! - Don Margolis

PharmaLive: Epistem plc and AstraZeneca Complete Plucked Hair ...
By valerio1
The Group's expertise is focused on the regulation of adult stem cells located in epithelial tissue, which includes the gastrointestinal tract, skin, hair follicles, breast and prostate. Epistem does not conduct research in the areas of ...
Valerio1's Weblog - http://valerio1.wordpress.com

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This category will pull the most relevant and up to the minute articles from Google News on the subject of ADULT STEM CELLS. 

Brief commentary on the articles will be included.

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Google News Alert for: adult stem cell - Feb 5, 2008


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To show you how far ahead of the USA all of Asia is, here is a typical piece from India. The first part of the article describes a fine use of embryonic stem cells (ANYTHING other than implanting these poisons into a human body is fine by me). The second half shows them starting to use adult stem cells successfully and unsuccessfully for certain diseases which will not ever be LOOKED AT by money-hungry American medical science. Take note, Michael J. Fox, since embryonic fakers must pretend that adult stem cells are worthless, by backing that which will kill you, you are effectivley destroying your ONLY chance at improvement. - Don Margolis

STEM the damage
Deccan Herald - Bangalore,India
Unlike usual bone marrow transplants where a litre of the liquid is drawn each time, with mesenchymal adult stem cells, all that is required is 30-60 ml ...
See all stories on this topic

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This article shows that there are more ways to find and more ways to use adult stem cells than science can keep up with. Next time you see an article in an American newspaper talking about embryonics, remember this when they say adult stem cells can't do as much as their cancer-causing embryonic stem cells. - Don Margolis

Gilbert doctor leads way for cardiovascular research group
East Valley Tribune - Mesa,AZ,USA
Dib recently earned approval for the second leg of his ongoing research that looks at using adult stem cells from thigh muscles to regenerate dead heart ...
See all stories on this topic

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posted new standard post 845pm eastern - Don Margolis

The State of Human Life
Town Hall - Washington,DC,USA
The development of adult stem cells is a great technical boon that may allow the culture to move beyond the ethical questions of the stem cell debate, ...
See all stories on this topic

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TO SIN BY SILENCE WHEN WE SHOULD PROTEST MAKES COWARDS OUT OF MEN.
-Ella Wheeler Wilcox

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Ducunt volentem fata, nolentem trahunt.
Fate leads the willing, the unwilling it drags.
Seneca the Younger ~ 50 A.D.

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Finnish patient gets new jaw from own stem cells http://www.abc.net.au/news/stories/2008/02/02/2152899.htm

Posted Sat Feb 2, 2008 5:16pm AEDT

Scientists in Finland said they had replaced a 65-year-old patient's upper jaw with a bone transplant cultivated from stem cells isolated from his own fatty tissue and grown inside his abdomen.

Researchers said the breakthrough opened up new ways to treat severe tissue damage and made the prospect of custom-made living spares parts for humans a step closer to reality.

"There have been a couple of similar-sounding procedures before, but they didn't use the patient's own stem cells that were first cultured and expanded in laboratory and differentiated into bone tissue," said Riitta Suuronen of the Regea Institute of Regenerative Medicine, part of the University of Tampere.

She told a news conference the patient was recovering more quickly than he would have if he had received a bone graft from his leg.

"From the outside nobody would be able to tell he has been through such a procedure," she said.

She said the team used no materials from animals - preventing the risk of transmitting viruses than can be hidden in an animal's DNA, and followed European Union guidelines.

Stem cells are the body's master cells and they can be found throughout the blood and tissues. Researchers have recently found that fat contains stem cells which can be directed to form a variety of different tissues.

Using a patient's own stem cells provides a tailor-made transplant that the body should not reject.

Complex procedure

Dr Suuronen and her colleagues isolated stem cells from the patient's fat and grew them for two weeks in a specially formulated nutritious soup that included the patient's own blood serum.

In this case they identified and pulled out cells called mesenchymal stem cells - immature cells than can give rise to bone, muscle or blood vessels.

When they had enough cells to work with, they attached them to a scaffold made out of a calcium phosphate biomaterial and then put it inside the patient's abdomen to grow for nine months. The cells turned into a variety of tissues and even produced blood vessels, the researchers said.

The block was later transplanted into the patient's head and connected to the skull bone using screws and microsurgery to connect arteries and veins to the vessels of the neck.

The patient's upper jaw had previously been removed due to a benign tumour and he was unable to eat or speak without the use of a removable prosthesis.

Dr Suuronen said her team had submitted a report on the procedure to a medical journal to be reviewed.

- Reuters

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Monash pioneers nano scaffold to rebuild nerve damage
31 January 2008

A Monash University PhD student has developed a new technique that could revolutionise stem cell treatment for Parkinson's disease and spinal cord injury.

David Nisbet from Monash University's Department of Materials Engineering has used existing polymer-based biodegradable fibres, 100 times smaller than a human hair, and re-engineered them to create a unique 3-D scaffold that could potentially allow stem cells to repair damaged nerves in the human body more quickly and effectively.

Mr Nisbet said a combined process of electrospinning and chemical treatment was used to customise the fibre structure, which can then be located within the body.

"The scaffold is injected into the body at the site requiring nerve regeneration. We can embed the stem cells into the scaffold outside the body or once the scaffold is implanted. The nerve cells adhere to the scaffold in the same way ivy grips and weaves through a trellis, forming a bridge in the brain or spinal cord. Over time, the scaffold breaks down and is naturally passed from the body, leaving the newly regenerated nerves intact," Mr Nisbet said.

Mr Nisbet said the existing processes released stem cells into the nervous system where they 'floated' around.

"Our studies show that stem cells anchored to a scaffold not only attach more easily, but rapidly adapt to their environment and regenerate effectively. We are very excited about the therapeutic outcomes that could be obtained from our research," Mr Nisbet said.

"We are at the interface of two once separate disciplines -- nanotechnology and stem cell research -- combining into a new exciting era of discovery which could be the first step towards a cure for conditions such as Parkinson's disease and spinal cord injury.

"Repairing damaged neural pathways is the holy grail of many researchers. It is a very long road to success, which will require small steps from many people, but it's wonderful to know we're making such a significant contribution here at Monash University," Mr Nisbet said.

The potential of Nisbet's scaffold design has captured the interest of colleagues. The University of Toronto in Canada and the Melbourne-based Howard Florey Institute are conducting further tests, with preliminary results showing strong potential.

Another collaboration, with the Mental Health Research Institute of Victoria, is investigating the use of scaffolds in the potential treatment of damaged brain nerve cells.

Mr Nisbet said biodegradable fibres were commonly used in biomedical sciences and regenerative technologies, but his technique of re-engineering them into a 3-D structure is a world first.

For high magnification images of the cellular structure or a copy of Mr Nisbet's paper contact Ms Samantha Blair, at samantha.blair@adm.monash.edu.au, +61 3 9903 4841.

http://www.monash.edu.au/news/newsline/story/1245

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Click here for:
A BRIEF HISTORY OF STEM CELLS

Click here for:
DON MARGOLIS ADULT STEM CELL-CARDIOLOGY QUOTES 2004-2007

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new posts start here...

For information about ASC treatments in El Salvador (at least ten different medical conditions) contact Mr. H. W. Trotter in Spanish, English, or German, at dorauno44@hotmail.com

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