Stem Cells Cure Boy With Graft Versus Host Disease (GVHD) At Duke

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In what has been an amazing week for Adult Stem Cell research, Kameron Kooshesh has been cured of his Graft Versus Host Disease (GVHD) after receiving Osiris' Adult Stem Cell product Prochymal in a clinical trial at Duke University.

Kameron, a young 14 year old boy had been suffering from Graft Versus Host Disease (GVHD) after receiving a bone marrow transplant to cure his Leukemia at the age of 9. GVHD is a disease in which the foreign cells introduced by the bone marrow transplant (taken from a human donor) attack the host's (the patient) organs and tissues because they do not recognize them.

Kameron had a severe gastrointestinal problem due to the GVHD. It was very bad and it limited him so much he couldn't even go up stairs.

He enrolled at a clinical trial run by Dr. Joanne Kurtzberg at Duke University. Dr. Kurtzberg is famous in this blog for the work she has done helping children with cerebral palsy with stem cells taken from their own cord blood.

At Duke, Kameron was given Prochymal, which is a stem cell product from Osiris made up of stem cells taken from the bone marrow of healthy human donors.

Here are the results:

“At one point, he couldn’t climb stairs,” His mother Janet recalled.

Now, Kameron has no problem climbing the stairs. He's also back in school full time. His recovery started quickly after taking part in a clinical trial at Duke.

“Within three weeks - it was just incredible,” said Kooshesh. “Absolutely incredible.”


“We've seen more than half the children we've treated respond with full resolution of the graft vs. host disease which is remarkable,” said Dr. Joanne Kurtzberg, Director of the Pediatric Blood & Marrow Transplant Program at Duke Children’s.

A "full resolution" sounds great to me and I'm sure it sounds even better to the young man, Kameron.

Click here to see the full story and a slow loading stem cell video

Click here to see more on Osiris' Prochymal to help GVHD

UPDATE:  Osiris just came out with a press release announcing results of their trial using Prochymal to treat Heart Attack patients.