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New Stem Cell Research for Unhealed Bone Fractures
A medical team is reporting new stem cell research using Adult Stem Cells to heal broken bones in the foot and ankle. The Adult Stem Cell product called "Trinity" was used to heal bone fractures in the foot and ankle of 21 people that failed to connect properly after the initial healing.
Clinical Results of Adult Stem Cells For Unhealed Foot and Ankle Fractures
Dr. Shannon Rush, of Palo Alto Medical Foundation presented his results of using Adult Stem Cells in the
Journal of Foot and Ankle Surgery for March, 2009:
A review was conducted of 23 patients who underwent implantation of mesenchymal stem cell allograft for revision foot or ankle surgery. Composed of viable mesenchymal stem cells derived from cadaveric donor tissue, the graft had osteogenic, osteoinductive, and osteoconductive properties, and was capable of direct new bone formation at the site of implantation.
In all of the cases, radiographic new bone formation was observed at the area of implantation and a 91.3% union rate was observed, and no evidence of graft rejection or complications associated with implantation were recorded.Let me try to translate that- the doctors took 23 patients who had broken bones or previous fractures in their foot or ankle that did not heal properly (or
nonunion is the clinical term). As a result, they had difficulty and/or pain when walking.
21 out of the 23 patients who were implanted with this adult stem cell product "Trinity" achieved "bone union" and healing which allowed them to walk in regular shoes with little or no pain after their casts were removed.
What is Trinity?
Trinity is a mixture of donated adult stem cells combined with crushed bone from a bone bank. It's full name is
Trinity Multipotential Cellular Bone Matrix.
I previously covered Trinity and how it was used for
spinal fusions. Most importantly, Trinity is already approved by the US FDA.
What This Means For Unhealed Bone Fractures
According to the
Trinity website:
Trinity is an effective alternative to autograft in virtually all orthopedic applications. Essentially, for every surgical indication where autograft would be selected by a surgeon to be a bone void fill or bone growth stimulator, Trinity can be used. Trinity is not intended to be be used as an autograft "extender." It is intended to be a substitute for autograft. An estimated 600,000 Americans suffer from unhealed bone fractures, so for any orthopedists or podiatrists or patients reading this- this is good news for you. Since it is FDA approved, I imagine if you wanted the "Trinity" adult stem cell product, it would be available for use- "ask your doctor".
Some of the Repair Stem Cell Institute's doctors already use adult stem cells for
bone fractures